BRAIN A JOURNAL OF NEUROLOGY DJ-1 and a-synuclein in human cerebrospinal fluid as biomarkers of Parkinson’s disease
نویسندگان
چکیده
1 Department of Pathology, University of Washington School of Medicine, Seattle, WA, USA 2 Department of Neurology, West China Medical School, Sichuan University, Chengdu, Sichuan, China 3 Department of Neurology, Oregon Health and Science University, Portland, OR, USA 4 Department of Psychiatry and Behavioural Sciences, University of Washington School of Medicine, Seattle, WA, USA 5 Mental Illness Research, Education, and Clinical Centre, Veterans Affairs Puget Sound Health Care System, Seattle, WA, USA 6 Department of Neurosciences, University of California at San Diego, San Diego, CA, USA 7 Parkinson’s Disease Centre and Movement Disorders Clinic, Department of Neurology, Baylor College of Medicine, Houston, TX, USA 8 Department of Neurology, University of Washington School of Medicine, Seattle, WA, USA 9 Department of Laboratory Medicine, University of Washington School of Medicine, Seattle, WA, USA 10 Department of Neurology, University of Chicago, Chicago, IL, USA 11 Department of Medical Biochemistry, University of Aarhus, Aarhus, Denmark
منابع مشابه
α-Synuclein and DJ-1 as Potential Biological Fluid Biomarkers for Parkinson’s Disease
Parkinson's disease (PD) is the most common form of movement disorder and affects approximately 4% of the population aged over 80 years old. Currently, PD cannot be prevented or cured, and no single diagnostic biomarkers are available. Notably, recent studies suggest that two familial PD-linked molecules, α-synuclein and DJ-1, are present in cerebrospinal fluid (CSF) and that their levels may b...
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